منابع مشابه
Alcoholic, Nonalcoholic, and Toxicant-Associated Steatohepatitis: Mechanistic Similarities and Differences
Hepatic steatosis and steatohepatitis are common histologic findings that can be caused by multiple etiologies. The three most frequent causes for steatosis/steatohepatitis are alcohol (alcoholic steatohepatitis, ASH), obesity/metabolic syndrome (nonalcoholic steatohepatitis, NASH), and environmental toxicants (toxicant-associated steatohepatitis, TASH). Hepatic steatosis is an early occurrence...
متن کاملToxicant-associated steatohepatitis: à propos a case of benzene exposure
An attempted interpretation of recurrent episodes of hepatitis in a girl at ages 6 and 13 years, which were followed by an interval of 35 years of apparent good health, is reported. A subsequent transient incidence of a halothane hypersensitivity reaction at age 48 years led to the disclosure of negative hepatitis A, B and C antigenicity. A tentative diagnosis may be reached if we accept, at it...
متن کاملThe Toxicant-wildlife Complex
Familiar vertebrate wildlife comprise less than five per cent of the animal kingdom. A major proportion of the other thousands of non-insect species are aquatic and will be increasingly exposed to a wide variety of manmade and natural chemicals. Effective management of this toxicant—wildlife complex demands general and simple means for the prediction and estimation of effects and hazards. Direc...
متن کاملMicroRNA deregulation in nonalcoholic steatohepatitis-associated liver carcinogenesis
Hepatocellular carcinoma (HCC) is the fastest-rising cause of cancer-related death in the United States. Recent epidemiological studies have identified nonalcoholic steatohepatitis (NASH), a progressive form of nonalcoholic fatty liver disease (NAFLD), as a major risk factor for HCC. Elucidating the underlying mechanisms associated with the development of NASH-derived HCC is critical for identi...
متن کاملResection of Nonalcoholic Steatohepatitis-Associated Hepatocellular Carcinoma: A Western Experience
Introduction. Hepatocellular carcinoma is now known to arise in association with nonalcoholic steatohepatitis. The aim of this study is to examine the clinicopathological features of this entity using liver resection cases at a large Western center. Methods. We retrospectively reviewed all cases of partial liver resection for hepatocellular carcinoma over a 10-year period. We included for the p...
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ژورنال
عنوان ژورنال: Toxicologic Pathology
سال: 2012
ISSN: 0192-6233,1533-1601
DOI: 10.1177/0192623312468517